General Hospital has been on the air for over sixty years, and that kind of history creates many unforgettable moments. Fans remember the weddings, betrayals, surprise returns, and tragedies.
But for the General Hospital actors who have lived these stories every day on set, certain scenes hit differently. These are not just the big ratings moments or the popular twists. These are the scenes that challenged them as actors or made them pause and feel something real.
When an actor plays the same character for years, they grow with the role. They carry the weight of old choices and past storylines, and that shapes how they play new ones. Some moments stay with them because of how personal the material felt or because the reaction from fans was overwhelming. Others remain memorable because the writing gave them something different to work with or pushed them emotionally.
These General Hospital scenes are not always loud or dramatic. Some are quiet and raw, and that is what makes them stick. These five actors from General Hospital have each picked one moment that still means something to them. It is a look behind the scenes into what really matters to the people who bring Port Charles to life.
5 General Hospital stars and their favourite moments from the show
1. Maurice Benard (Sonny Corinthos)

Maurice Benard has always spoken openly about how personal Sonny’s bipolar storyline felt. In 2006, Sonny had a breakdown in court while facing charges, and that moment became one of Maurice’s most difficult but rewarding scenes. It gave him a chance to bring truth to a diagnosis he shares with the character.
He has lived with bipolar disorder in real life, so he knew how important it was to get the emotion and weight of the scene right. The scenario did not rely on dramatic tricks. It focused on Sonny unraveling in a way that felt grounded and honest. Fans responded with letters and support, and Maurice still says it is one of the most potent reactions he has ever had.
The moment also changed Sonny. It opened the door for future stories to show his struggles without making him look weak. It turned his illness into part of his strength.
2. Laura Wright (Carly Spencer)

Laura Wright has often picked Carly and Sonny’s 2015 wedding as a personal highlight. This wedding stood out because it felt like both characters finally understood what they were walking into. Carly had stopped chasing chaos and had started choosing something steady.
The build-up had years of weight behind it. The scenes didn’t need shock value because they came from a long history of breakups and reunions. Laura has said she felt every part of those scenes because they reflected how far Carly had come. This version of Carly wanted Sonny for who he was and not who she hoped he would become.
It was not a fairy tale ending, but something more grounded, and that made it matter. The scenes gave both characters a moment of peace, and the audience could see how hard they had fought to get there. Laura said it finally felt earned.
3. Finola Hughes (Anna Devane)

Finola Hughes often mentions the moment Anna learned Robin was HIV-positive in the 1990s as a turning point in her career. That story was more than just a plot. It dealt with something real that impacted families across the world at the time.
Anna had no control over the news. The scenes focused on the confusion and fear that came with learning your daughter had a life-altering condition. Finola has said she respected how the writers gave space to the emotion instead of speeding through it. It gave her something personal and grounded to play.
Fans wrote to the show, sharing how much it helped them feel seen or less alone. The show also gave Anna’s character a moment of raw honesty that had nothing to do with action or danger. It was just a mother trying to understand something she never thought she would have to face.
4. Genie Francis (Laura Collins)

Genie Francis calls the 1993 return of Luke and Laura one of the most layered moments she has ever played. Laura had been off-screen for years, and this was not just about bringing her back. It was about showing that she had changed.
She returned with a past shaped by trauma. She had survived and had become a mother. Laura’s homecoming was filled with tension because she had to face what she had left behind. Genie said she liked that the character came back stronger and more serious than before. There was no reset button.
The scenes gave Laura room to be more than just half of a super couple. She was now a woman with history and loss. Fans responded well because it felt like a new chapter instead of a repeat of the old one. Genie said it let her grow as an actor and as the character, too.
5. Dominic Zamprogna (Dante Falconeri)

Dominic Zamprogna always comes back to the moment Dante was shot by Sonny. That twist hit hard because Sonny did not know he was shooting his own son. Dante was undercover and trying to take Sonny down when the scene unfolded.
There was no dramatic pause. The gun went off, and everything changed. Dominic has said that scene pushed him in a way few others have. It gave him the chance to show pain, shock, and betrayal all in one beat. The fallout changed both characters. Sonny had to deal with what he had done.
For Dante, it meant he was no longer just a cop with a mission. He became part of the Corinthos family story. That scene gave Dominic a place at the center of the show’s long-running conflicts. It also made Dante a character who had something real to carry forward in every scene after.
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