10) Robert De Niro and Mickey Rourke

Robert De Niro and Mickey Rourke had reportedly been feuding since the making of Angel Heart (1987), with Rourke claiming De Niro had acted dismissively to him. Years later, Rourke accused De Niro of actually blocking his casting in The Irishman, which reignited their animosity. De Niro has kept quiet on the issue to date, but Rourke's audible criticism suggests lingering bitterness. The rivalry speaks well of how slighted Hollywood professionals can envision that slight turning into a long-term feud, even between two great actors.
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Edited by Sarah Nazamuddin Harniswala