13) Jake Gyllenhaal (Love and Other Drugs, 2010)

Jake Gyllenhaal brought a mix of charisma and emotional depth to Jamie Randall in Love and Other Drugs. He portrayed Jamie’s transformation from a charming but self-centered pharmaceutical rep to a man deeply in love with incredible authenticity. Gyllenhaal’s chemistry with Anne Hathaway elevated the film, making their romance feel raw and real.
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Edited by Abhimanyu Sharma