Wrestler Alice "The Dominator" Gunderson was originally hired by Sonny Corinthos to protect the Quartermaine family from the threat posed by mob rival Joseph Sorel. Lila Quartermaine bonded with Alice and kept her on staff as a housekeeper after the danger had passed. During her time serving the family, Alice openly shared her opinions regarding certain members of the Quartermaine clan but always remained loyal to the family. Alice openly favored Edward and Monica over Tracy and her allegiance was awarded in the form of ELQ stock upon Edward's death. Alice also doted upon her crush, Tracy's husband Luke Spencer. When Edward's great-grandson Michael took his place within the family, Alice favored him over Tracy as well.

After serving the Quartermaines for several years, Alice was considered family. She was involved in numerous inter-family squabbles, Thanksgiving pizza, and battles for control over ELQ. When Alice was diagnosed with heart disease and required a heart transplant, the family rallied around her with Tracy at the helm. Tracy promised to find Alice a new heart in exchange for Alice's silence regarding Tracy's secret plans to take over ELQ.

Alice and the Quartermaines were relieved that a donor had been found after mobster Mickey Diamond was declared brain-dead. Alice's condition worsened while the hospital tried to contact Mickey's family. Unbeknownst to everyone, Sonny Corinthos paid an actress to pose as Mickey's sister and she authorized the transplant. As Alice recovered, she told Michael that Tracy and Luke were plotting to get ELQ.