Absentia Season 2 ending explained: Emily uncovers a deadly serum experiment and Alice’s betrayal

Absentia (Image Source: Prime Video)
Absentia (Image Source: Prime Video)

Absentia Season 2 began with Emily Byrne (Stana Katic) looking for peace. She needed clarity after her harrowing kidnapping and trauma from Season 1. Her search for the truth quickly pulled her into a new and dangerous conspiracy. The ten episodes of the season built toward a dramatic and shocking finish.

This season focused on Emily's struggle to adjust to her old life while pursuing justice for the wrongs done to her. She worked to reconnect with her son, Flynn, and her ex-husband, Nick. All the while, Emily hunted the people responsible for her continued torment. The show brought intense personal drama and a twisting, high-stakes criminal plot to the screen.


Absentia Season 2 ending explained

Absentia (Image Source: Prime Video)
Absentia (Image Source: Prime Video)

The serum and the scientist

Absentia Season 2 ending explained: The core of the plot centered on a terrible experiment. Dr. Oduwale was Flynn’s therapist. The doctor was secretly making a "resilience serum." He needed a unique blood sample for his work. He received the blood from Laurie, the main villain from Season 1. Laurie had kidnapped Emily and then sent the blood to the doctor.

Dr. Oduwale used Emily's blood to develop his serum. He tortured Emily to find ways to heighten her resilience. Then he tested the serum on patients. The serum only worked on Rex Wolfe, a former soldier. The tests failed on six other civilian patients. So, Dr. Oduwale had Rex murder the others to hide the proof of his work. He also had Tommy murdered. Tommy had gotten too close to finding the facts. Emily pursued Dr. Oduwale to understand her unwilling part in his dark work.


Alice’s secret role

The greatest surprise of Absentia Season 2 involved Alice Durand. Alice was Nick’s current wife. She acted as a kind and trusted figure to Flynn. Emily eventually learned that Alice had been working with Dr. Oduwale the entire time. Alice worked as the doctor’s assistant in the serum research. She inserted herself into Nick’s life by posing as Flynn's therapist. This deception let them continue their dark experiments without anyone suspecting.

Alice killed Dr. Oduwale when Emily got too close to finding the truth. She claimed she did it to protect Emily. She also denied knowing the research was linked to Emily’s kidnapping. Alice insisted she thought they were only "monitoring stress." Emily quickly saw that Alice was lying. This exposed Alice as a fraud who had stolen Emily’s life and then harmed her further. This betrayal became the dark climax of Absentia Season 2.


The confrontation and final act

Absentia (Image Source: Prime Video)
Absentia (Image Source: Prime Video)

Alice tried to run away when she knew Emily would expose her. Emily found her and forced a long-awaited confrontation. Alice insisted her feelings for Nick and Flynn had turned real. Emily chose to let her go. Emily put her gun away to end the standoff.

Alice still kept her gun pointed at Emily. Alice walked closer to Emily, but she did not fire. Then Gunnarson, the new head of the FBI branch, shot Alice. Alice died instantly in the street. Absentia Season 2 ending explained: Alice died without ever facing Nick and Flynn about her secret.

Emily told her family that Alice had died. She kept Alice's full betrayal a secret from them. Nick and Flynn still believe Alice was a good, innocent person. The final events of Absentia Season 2 left many viewers with new questions about Gunnarson's motive for the sudden shooting.


Looking ahead

Emily found justice for the murder of her biological mother, Valerie Chandris. She also stopped Dr. Oduwale's dangerous serum work and got justice for Tommy’s death. The true effect of Alice's actions stayed hidden from Nick. Absentia Season 2 sets up new drama for the next season.

Edited by Zainab Shaikh