Blindspot cast and character guide: Who plays whom in the drama series?

Blindspot. (Image via. @nbcblindspot, instagram)
Blindspot. (Image via. @nbcblindspot, instagram)

Blindspot begins with a woman's body full of tattoos being found in a duffel bag. This thrilling NBC show, spanning 2015 to 2020, follows the protagonist, Jane Doe, as the FBI try and decode her inked clues to open up a web of conspiracies.

Interested to know who brings these characters to life? Read below to find out more.


Blindspot cast and character guide:

Jaimie Alexander as Jane Doe/Remi

Jaimie Alexander plays the character of Jane Doe, the heart of Blindspot's mystery. Found with no memory and covered in tattoos, Jane's journey is a rollercoaster.

The American Heart Association's Red Dress Collection Concert 2025 - Source: Getty
The American Heart Association's Red Dress Collection Concert 2025 - Source: Getty

As Remi, her past self, she's a fighter tangled in dark secrets. Alexander's performance holds Jane's vulnerability and strength, making her a standout character.

She is known for projects like Agents of S.H.I.E.L.D. & Kyle XY.


Sullivan Stapleton as Kurt Weller

Sullivan Stapleton plays Kurt Weller, the FBI agent drawn into Blindspot's mystery when a tattoo links to his name. Weller's presence anchors the team, but his growing bond with Jane sparks a romance.

2016 Summer TCA Tour - NBCUniversal Press Tour Day 1 - Arrivals - Source: Getty
2016 Summer TCA Tour - NBCUniversal Press Tour Day 1 - Arrivals - Source: Getty

Stapleton bringsheart to Weller, whose life has been shaped by forces since his youth. His search of truth in Blindspot drives the story forward, balancing his personal stakes with high-stakes investigations related to the mystery.

He is known for projects like The Secret Life of Us & 300: Rise of an Empire.


Michelle Hurd as Ellen Shepherd

Michelle Hurd acts as Ellen Shepherd, the mastermind behind in the show. As Jane and Roman's adoptive mother, Shepherd's tactics and military background make her a formidable enemy.

2024 FAN EXPO New Orleans - Source: Getty
2024 FAN EXPO New Orleans - Source: Getty

Hurd's character is a villain who believes her actions serve a greater good. Through flashbacks, Blindspot shows Shepherd's manipulative hold over her children, creating a complex antagonist whose influence lingers across seasons, challenging the FBI at every turn.

She is known for projects like Law & Order: Special Victims Unit & The Glades.


Luke Mitchell as Roman

Luke Mitchell brings Roman, Jane's brother, to life in the show. With a knack for mind games, Roman's loyalty sways between family and revenge.

Mitchell's nuanced performance makes Roman both a villain and a victim. He is a character fans love and hate. His schemes, like adding glowing tattoos to Jane, keeps the show's tension high until the character meets his end.

He is known for projects like H₂O: Just Add Water & Chicago Med.


Robert Brown as Edgar Reade

Robert Brown plays Edgar Reade, an FBI agent in Blindspot's New York office. Skeptical of Jane's tattoos, Reade's loyalty is tested by personal ties, like his love for Sarah.

Brown plays in Reade's emotionality, from his romance with Tasha Zapata to his tragic death in a strike. Reade's arc in the show leaves a lasting impact on the team.

He is known for projects like Finding Forrester & Don Jon.


Audrey Esparza as Tasha Zapata

Audrey Esparza's Tasha Zapata is a tough, determined FBI agent in the show with a hidden gambling addiction.

In the later seasons, Zapata joins the CIA and becomes a mother, adding layers to her complex journey.

She is known for projects like Power & Black Box.


Ashley Johnson as Patterson

Ashley Johnson plays Patterson, Blindspot's tech genius who figures out the meanings behind Jane's tattoos. She starts her journey off in the lab, and she later grows into a field agent.

Johnson's charm brings warmth to Patterson's wit.

The show reveals her to be Bill Nye's daughter, adding a quirky twist. Her growth into a tough, empathetic leader makes her a fan favorite across the series.

She is known for projects like Growing Pains & The Killing.


Mary Elizabeth Mastrantonio as Madeline Burke

Mary Elizabeth Mastrantonio plays Madeline Burke, a villain in the later seasons of the show. A powerful Global stockholder, Burke orchestrates a blackout and frames Weller's team to seize control of federal law enforcement.

Her schemes make her a threat, keeping the stakes high until the final season.

She is known for projects like The Abyss & The Perfect Storm.


Blindspot's cast is what makes the show what it what it is. From Jaimie Alexander to Mary Elizabeth Mastrantonio, each actor crafts unforgettable characters that the fans get to see on screens.

Spanning across five seasons, Blindspot blends mystery and heart, making it a binge-worthy watch for fans who love crime dramas.


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Edited by Zainab Shaikh