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NBC's Brilliant Minds Season 2 is expanding its universe with four new stars, forming an exciting guest lineup for the upcoming season.
The medical drama series created and written by Michael Grassi is inspired by British historian and author Oliver Sacks' books An Anthropologist on Mars and The Man Who Mistook His Wife for a Hat.
According to Variety, Porsha Williams, Molly Bernard, Connor Tomlinson, and Laura Vandervoort have all joined as guest stars for the upcoming season, which is set to premiere on NBC on September 22, 2025.
These four stars will join the Brilliant Minds Season 2 fellow cast additions, Bellamy Young and Al Calderon. Season 2 will also feature returning cast from Season 1, led by Zachary Quinto as Oliver Wolf, and followed by Perry, Ashleigh LaThrop, Alex MacNicoll, Aury Krebs, Spence Moore II, Teddy Sears, and Donna Murphy.
The official synopsis for the show reads as follows:
“Brilliant Minds follows a revolutionary, larger-than-life neurologist (Quinto) and his team of interns as they explore the last great frontier – the human mind – while grappling with their own relationships and mental health.”
More on this in our story.
Brilliant Minds Season 2 adds four new cast members
Porsha Williams (The Traitors, The Real Housewives Ultimate Girls Trip) and Laura Vandervoort (V Wars, Supergirl) will both guest star in the Brilliant Minds Season 2 premiere episode. Williams will play Bitsy, and according to her character description via Variety:
“[She is] an affluent Upper West Side housewife who sees Dr. Carol Pierce (Tamberla Perry) at her private practice. She knows all the gossip about everyone, on every medical board in New York City.”
Vandervoort will play the role of Cynthia Grudko, an MMA fighter's wife and mother of two children. When her husband Tommy starts to experience strange symptoms, she will fight for her husband's health, even if it means going against his coach.
Actors Molly Bernard (Younger, Chicago Med) and Connor Tomlinson (Love on the Spectrum US) will appear respectively in Brilliant Minds Season 2 Episodes 2 and 3. Bernard will play the character of Lauren Brooks, whose character description reads as follows:
“A young professional looking for love who finds herself in her worst nightmare: she has a mental health crisis while filming a reality dating show… and everyone is watching.”
Lastly, Tomlinson will play Tom in Brilliant Minds Season 2, who lives in a group home and has a fondness for the spy genre. He will cross paths with the titular team when they are out solving a medical mystery.
While it is unlikely that all these new characters will cross paths in the show's universe, they do make for an exciting lineup, hinting that Oliver Sacks' book universe will surely expand in the upcoming season. The team will investigate new mysteries in the upcoming season while tackling their own relationships in their respective personal lives.
Catch the Brilliant Minds Season 2 premiere on NBC on September 22, 2025, at 10/9c.
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