Doc Season 2 dropped on Sunday, September 14, 2025, at 9:00 p.m. Eastern Time and 8:00 p.m. Central Time, per IMDb, for a special premiere. However, Season 2 Episode 1 will air, for the second time, on Tuesday, September 23, 2025. With this, the show settles into its regular weekly time slot and is scheduled to release every Tuesday on Fox.
Doc is a medical drama, based on the Italian series titled Doc – Nelle tue mani, loosely inspired by the real-life story of Dr Pierdante Piccioni. The show blends hospital drama with personal stories, combined with the ethical and emotional challenges that the doctors face as they take care of their patients.
Read on for the complete streaming schedule of Season 2.
Here is the release schedule for Doc Season 2.
As mentioned, although Season 2 premiered on September 14, the show has returned for its regular airing time slot of 9-10 ET/PT for the fans to watch on September 23, 2025, with the rest of the episodes releasing every Tuesday. This marks the time of release of Episode 2 ("Delusions of Grandeur") as September 30 and Episode 3 ("New Blood") as October 7, 2025.
Refer to the list below for more release dates of Doc episodes.
- Season 2, Episode 4: “Something to Prove” on Tuesday, Oct. 14
- Season 2, Episode 5: “Tightrope” on Tuesday, Oct. 21
- Season 2, Episode 6: “Saints and Sinners” on Tuesday, Oct. 28
- Season 2, Episode 7: “Shock to the Heart” on Tuesday, Nov. 4
- Season 2, Episode 8: “What I Did for Love” on Tuesday, Nov. 11
Season 2 consists of 22 episodes in total, and after the episode airs on Fox, it becomes available to stream on Hulu and Disney+ the next day, per reports.
What else do we know about Doc Season 2?

Season 1 of the show sets up for a banger Season 2 with Dr Amy recovering from a tragic car accident that caused memory loss. She is determined to regain her memory and reclaim her position as chief of internal medicine at Westside Hospital. The hospital has also, for now, replaced her with Dr Joan Ridley. Dr. Amy has re-joined the hospital as an intern, as Dr Joan challenges her to prove her dedication.
Therefore, the season focuses on Dr Amy's struggle to overcome these professional and personal obstacles and win back her position and memory.
The synopsis of Season 2, Episode 1 reads,
"Amy's past comes back to haunt her when a desperate father sacrifices everything to secure his daughter's heart transplant."
The show is co-produced by Sony Pictures Television and Fox Entertainment Studios with popular names such as Barbie Kligman, Hank Steinberg, Erwin Stoff, Russell Fine, John Weber, Frank Siracusa, Carol Barbee, and David Foster as the showrunners and Executive producers. This gives the show strong backing and supervision. The fans can expect an equal level of emotional drama and authentic storytelling like it was in Season 1.