Watson Season 1 ending explained: Moriarty’s death and Holmes’ fate

The finale of Watson airs TOMORROW on CBS! ( Image via Instagram / @watsoncbs )
The finale of Watson airs TOMORROW on CBS! ( Image via Instagram / @watsoncbs )

CBS's Watson reimagines the Sherlock Holmes world from another vantage point—through the eyes of a post-Holmes Dr. John Watson, now operating a specialty medical clinic in Pittsburgh.

Throughout its first season, Watson plays out as a blend of mystery, medical drama, and psychological nuance. The show slowly peels away layers of Watson's grief over Sherlock Holmes' death and draws an assortment of offbeat patients, medical mysteries, and sinister figures from Watson's history.

The Season 1 finale, a two-part episode titled "Your Life's Work," answers many of the season's simmering questions. The viewer witnesses not only the breakdown of a serious health crisis but also Watson's emotional and philosophical reckoning.


Moriarty's fate in Watson Season 1: The end of a master manipulator

One of the big storylines of the season was the return of James Moriarty (Randall Park), whose real identity had been a mystery throughout the series. As the finale demonstrates, Moriarty was not only alive but had been manipulating much of the action behind the scenes himself. His manipulations included personal attacks on Watson and a more sinister plot with genetically engineered diseases.

But, unlike rumor and speculation, Moriarty does not survive the season finale. Following an emotionally charged battle with Watson, he is deliberately infected with the same bioengineered disease he used to hurt others. Watson, though clearly conflicted, decides not to save him. Instead, he remains with Moriarty as he passes away—a deliberate, symbolic act of closure.

It is not merely a physical death for Moriarty but also an emotional transition for Watson, severing one of the final threads to his previous life.


The Croft Brothers' crisis in Watson Season 1: A moral and medical dilemma

Another major plotline in the finale is Adam and Stephen Croft, twins played by Peter Mark Kendall, who get seriously ill from Moriarty's bioengineered disease. The staff at the Holmes Clinic, led by Watson, find themselves in a no-win situation: there is but one dose of the cure. This forces the staff into the untenable position of having to confront impossible ethical decisions—who lives, and who decides?

The story is both a literal and metaphorical crucible for the clinic. It presents the show's very raison d'être: not just to unravel mysteries, but to confront human suffering, doubt, and responsibility. It's a crisis created not by poisoned water mains, as some early reports falsely suggested, but in a targeted biological attack designed to challenge Watson to his limits.

This is where Watson enters full-on ethical drama mode, plumbing questions of identity, personal connection, and professional judgment. The final determination of which brother receives the cure is arrived at with a high emotional cost, making the Holmes Clinic more than a place of treatment. It is a ground zero for the moral battlefield and medicine.


Sherlock Holmes in Watson Season 1: Still missing, still haunting

Sherlock Holmes' absence is looming over the season finale just as it has been looming all season. Rumored to have perished after the infamous Reichenbach Falls, Holmes' fate is unknown. The show does not provide conclusive flashbacks, clues, or hints that he is alive or that he's left Watson cryptic messages.

All that notwithstanding, the symbolic actions are solid. Watson locks up the "Holmes box," a physical surrogate for their combined past, at the end of the finale. This introspective, emotive action does not declare Sherlock deceased, nor does it rule out his return.

Instead, the series treads exceedingly carefully on the high wire of resolution and intrigue. It presents the audience with just enough ambiguity to speculate without crossing over into fan service or misleading teasers.


Watson's personal reckoning and future in Watson Season 1

Besides the external conflict, the finale also marks internal transformation for Dr. Watson. Amidst his fight with the guilt of Moriarty's death and the Croft brothers' crisis, Watson undergoes a personal turning point. His budding romance with pediatric oncologist Dr. Laila is a healing step. Contrary to a lot of detective fiction that hangs on isolation, Watson steps into emotional vulnerability.

He does not say he's leaving medicine behind for detection, nor does he do any of that sensational transformation. But putting away the Holmes memorabilia and choosing to invest in a new personal connection signals a conscious choice to stay present. This subtle plot twist tells us that while Watson's attachment to Holmes and Moriarty is important, they no longer define him.


Season 2 plans: What's next for Watson?

CBS has renewed Watson for season two, with a confirmed return as part of the 2025–2026 primetime lineup, airing Sundays at 10 p.m. While Morris Chestnut is expected to return in his role as Watson, official cast announcements have yet to be released.

As is revealed by showrunner and EP Craig Sweeny, the series will go on with its Sherlockian themes. There is no definitive plan to bring back Sherlock Holmes as a main character, however. The finale's setup is thoughtful in establishing a new chapter with an equally similar tone for the series while opening up space for new stories to cut through without being too reliant on hallowed Holmes canon.

This leaves a few avenues open for storytelling—will Watson pursue more unusual medical afflictions, fight more residual effects from Moriarty's schemes, or finally encounter indications that indicate Holmes might actually still be alive? In any case, Season 2 promises to expand on the premise without sacrificing its thoughtful, grounded style.


The Watson Season 1 finale balances resolution and open-endedness well. Moriarty's demise offers conclusive closure to a season-long narrative, but Sherlock Holmes' continuing absence leaves it up in the air. The Croft brothers' crisis adds emotional depth, and Watson's personal decisions suggest a subtle but profound change.

Above all, the finale eschews spectacle or cliffhanger effect. Instead, it brings the season to a close on an emotional basis with narrative self-control. For a show perched precariously on the fulcrum between an old-fashioned detective series and a new-fashioned medical ethics series, this kind of closing appears to be true to form.

Also read: Watson Episode 11 recap: The past returns to haunt Watson

Edited by Sezal Srivastava