Lauren Katherine "Kiki" Jerome followed her boyfriend, Morgan Corinthos, to Port Charles after his parents forced him to return home. Kiki and Morgan had met online while frequenting illegal gambling sites, and Kiki had encouraged Morgan to bet more after he accumulated several thousands of dollars in gambling debt. Morgan's brother and parents quickly learned of Kiki's involvement in Morgan's financial troubles and were not thrilled with their relationship. However, Kiki's mother, Ava, supported their association and encouraged Kiki to visit Morgan in Port Charles.
While Kiki visited Morgan, they stayed with Morgan's older brother Michael. While Kiki was there, her mother visited and revealed that Kiki was part of the wealthy Quartermaine family and that her father was alive. Kiki was shocked by the revelations and bonded with Michael as he shared some of the similar family drama he had lived through. As they spoke, they traded stories related to their respective fathers, unaware that their fathers were brothers. Kiki and Michael shared a kiss but regretted it immediately afterwards when they learned that they were cousins.
Kiki moved in to the Quartermaine mansion with her new family and Morgan moved with her, unaware of the kiss she had shared with his brother. As Kiki tried to forget about Michael, she met Franco, the man she believed to be her father and was shocked to discover that her mother had reunited with him. Kiki tried to avoid her parents and Michael but her thoughts remained on her cousin. She also worried Franco after he was the victim of an assault and was diagnosed with a brain tumor. While at the hospital, she met a doctor from her mother's past named Silas Clay, unaware that he was actually her father. Unbeknownst to Kiki, Morgan knew the truth that she was not related to Michael and he feared that she would chose end her relationship and chose to be with Michael when she learned the truth. While Kiki remained in the dark, she accepted Morgan's marriage proposal.
Shortly after the proposal, Morgan and Kiki married at the courthouse. Immediately after the ceremony, Michael arrived and announced that Kiki was the daughter of Silas Clay and was not related to the Quartermaine family. Michael questioned if Morgan had known the truth and Kiki believed her husband when he claimed that he was unaware of Kiki's paternity. Kiki was furious with Ava for her lies but agreed to attend a party hosted by her mother to celebrate her marriage to Morgan. At the party, Morgan's father admitted that Morgan had told him that Michael and Kiki were not related and he apologized for keeping Morgan's secret. Kiki was disgusted with Morgan's betrayal and ended their marriage.
After the marriage ended, Kiki and Michael admitted their feelings for one another and moved in together. Kiki worried about how Morgan would handle her new relationship but her concern waned when she learned that Morgan was residing with her mother and that they were lovers.