Grey's Anatomy Season 22, Grey's Anatomy Season 22 Episode 3: Grey's Anatomy Season 22 Episode 3: Release date news, streaming details and more

Grey's Anatomy Season 22 is off to a heartbreaking start as the hit drama series continues to draw in fans with memorable performances and incredible writing. After the previous emotional episode, the series returns with its episode 3 on Thursday, October 23, 2025, at 10 PM ET on ABC. The episodes will also be available to stream on Hulu the next day.

The series revolves around the medical professionals at Grey Sloan Memorial Hospital as they navigate through their challenging personal and work lives. Grey's Anatomy Season 22 Episode 3 titled ‘Between Two Lungs’ will see the team attempt a high-risk lung transplant surgery. Dr. Bailey will be working on treating a trauma patient.

Grey's Anatomy Season 22 Episode 3 release date and streaming details

Grey’s Anatomy Season 22 Episode 3 titled ‘Between Two Lungs’ will release on Thursday, October 23, 2025, on ABC at 10 PM ET/9 PM CT. The episodes will be available on the streaming platform Hulu the day after.

The pricing for Hulu has been increased in the U.S. with the standard plan priced at $11.99/ per month. Hulu Premium plan with no ads is available at $18.99/per month. Disney+, Hulu and ESPN Unlimited bundle with ads is available at $29.99/per month for 12 months.

Grey's Anatomy Season 22 Episode 3 cast

The regular characters will be returning to reprise their celebrated roles in Grey's Anatomy Season 22 episode 3. Here is a look at some of the cast.

Ellen Pompeo – Dr. Meredith Grey

Chandra Wilson – Dr. Miranda Bailey

James Pickens Jr. – Dr. Richard Webber

Kevin McKidd – Owen Hunt

Camilla Luddington – Dr. Jo Wilson

Jason George – Ben Warren

Kim Raver – Dr. Teddy Altman

Chris Carmack – Dr. Atticus Lincoln

Alexis Floyd – Simone Griffin

Harry Shum Jr. – Dr. Benson “Blue” Kwan

Adelaide Kane – Dr. Jules Millin

Niko Terho – Lucas Adams

Caterina Scorsone – Dr. Amelia Shepherd

What happened in Grey's Anatomy Season 22 Episode 2?

In the previous episode of Grey’s Anatomy, we saw the team at Grey Sloan Memorial Hospital still coming to terms with the aftermath of the explosion, which resulted in the death of Dr. Monica Beltran (played by Natalie Morales). Amelia and Jules especially are seen reeling from losing the vital member of their team.

Maggie (played by Kelly McCreary) and Meredith step in to help Amelia through the emotional chaos. Amelia blames herself for the incident as she felt she should have disagreed to go ahead with the first surgery. Maggie will also reveal that she went through IVF with sperm donor and is pregnant. At the end of the episode, Amelia decides to take a sabbatical from the hospital, which Richard agrees to.

Jules, who was with Beltran during the final hours, is suffering from trauma. It starts affecting her work as well and Winston helps her cope with the stress. She decides to finally grieve Beltran and starts healing from the trauma.

Link, on the other hand, is also seen struggling. He is ridden with guilt and gets angry at Jo for treating him like a patient. Meanwhile, there is a lot of tension between Lucas and Simone. It is revealed that the random person that Simone slept with while they were on a break is the new intern, Wes.

What to expect in Grey's Anatomy Season 22 Episode 2?

The episode ‘Between Two Lungs’ will see the surgical team coming together for a lung-transplant. The procedure is not only high-risk but the fight against time makes it even more serious. The critical case puts immense pressure on the surgical team, who are trying to find ways to save the patient.

Dr. Bailey, an expert at multitasking cases at the hospital, faces one of the more crucial challenges in her career as she treats a trauma patient. As the stakes run high, Bailey tries to treat the patient to the best of her abilities.

The logline of the episode as per Rotten Tomatoes states,