Prison Break maintained suspense among viewers over the years due to its action-packed plot, complex family dynamics, and high-stakes drama. The show revolves around the daring adventures of Michael Scofield, who vows to free his brother, Lincoln Burrows, from prison grounds since he has been wrongfully condemned to death.
The characters, including the brothers and their allies, as well as their enemies, became familiar to the fans. Twenty years later, people still return to the show, and it has found fans among the new generation as well.
The Prison Break cast features stars such as Wentworth Miller as Michael and Dominic Purcell as Lincoln, as well as key supporting actors including Sarah Wayne Callies, Robert Knepper, and Amaury Nolasco.
Wentworth Miller plays Michael Scofield

Michael is a brilliant engineer with complicated feelings. Miller was selected to play the role a week before filming after he had impressed the creators with his audition.
Dominic Purcell portrays Lincoln Burrows

Lincoln Burrows is sentenced to death for a crime he didn’t commit. Dominic Purcell was cast just three days before filming began, and surprised the creative team by arriving on set shaved close, instantly matching the intended physical contrast with his co-star.
Main supporting characters and who played them

- Sarah Wayne Callies is Dr. Sara Tancredi (later Scofield), the prison doctor who becomes Michael’s partner.
- Amaury Nolasco plays Fernando “Sucre” Sucre, Michael’s loyal cellmate.
- Robert Knepper is Theodore “T-Bag” Bagwell, a dangerous and manipulative inmate.
- Wade Williams portrays Brad Bellick, the tough prison guard overseeing Fox River.
- Rockmond Dunbar plays C-Note, another inmate, known for using his street smarts to survive.
- Paul Adelstein is Paul Kellerman, starting as a Secret Service agent and evolving into a complex figure in the conspiracy.
- William Fichtner plays FBI agent Alexander Mahone, tasked with capturing the escaped prisoners.
- Peter Stormare is mob boss John Abruzzi, an inmate Michael needs help from.
- Marshall Allman plays L.J., Lincoln’s son, who becomes part of the drama.
- Additional characters, such as Sofia Lugo, James Whistler, Lechero, Gretchen Morgan, Sheba, Jacob Ness, and Whip Martin, become important in later seasons.
Where are the Prison Break cast members now?

- Wentworth Miller (Michael) moved into shows like The Flash and Legends of Tomorrow, then turned to writing and stepped back from straight roles after coming out.
- Dominic Purcell (Lincoln) also appeared in DC shows and will reunite with Miller in the new action series Snatchback.
- Robin Tunney (Veronica) starred in The Mentalist after Prison Break.
- Sarah Wayne Callies (Dr. Sara) had a big role in The Walking Dead and now co-hosts a Prison Break rewatch podcast.
- Amaury Nolasco (Sucre) continued acting in TV and movies.
- Paul Adelstein (Kellerman) has transitioned into Shondaland drama shows and plays, and he’s set to appear in the upcoming film Crime 101 in 2026.
- Robert Knepper (T-Bag) appeared in shows like iZombie and The Hunger Games films, though he faced assault allegations in 2017, which he has denied.
- Rockmond Dunbar (C-Note) left 9-1-1 over a vaccine mandate.
- William Fichtner (Mahone) continues working in TV and film, with upcoming roles like in Netflix’s Beef.
A Hulu reboot of the show is in production. It’s set in the same world but features entirely new characters, such as an ex-soldier turned corrections officer and a politician; no original cast member has confirmed return.