Who’s who in Big Mouth Season 8: Cast and cameo guide to Netflix’s final Season

Netflix's animated coming-of-age sitcom Big Mouth is back with its eighth and final season starting May 23, 2025. The show is co-created by Andrew Goldberg, Nick Kroll, Mark Levin, and Jennifer Flackett and debuted in 2017.

The sitcom follows a middle-school teenager, Nick Birch, and his four friends, who navigate the murky and uncomfortable waters of puberty and learn about s*x and growing up together.

Their puberty-filled lives often clash with unusual things and people, who help them understand the challenges of their age, both physically and mentally.

Big Mouth Season 8 will see the return of the main and supporting cast, who will reprise their respective characters for the final season. The sitcom will also see some cameos from new and familiar faces.

Here's the complete cast and character guide for Big Mouth Season 8.

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Big Mouth Season 8: The main voice cast will return for the final season

The main voice cast for Season 8 will reprise their respective characters for the final season.

1) Nick Kroll- Nick Kroll, the sitcom's co-creator, has been the main cast member since its premiere. He voices many characters, including Nick Birch, the self-centred and insecure protagonist.

In addition, Kroll will also voice for Lola, Maury, Coach Ben, Rick, Maurice, and Stu. Kroll is famous for his many sketches, including his comedy show, Kroll Show.

2) John Mulaney- Another main cast member of the show, comedian John Mulaney, will reprise his role as Andrew Glouberman, Nick's best friend in the sitcom.

The pair will continue their pubescent hormonal adventures in Big Mouth Season 8. Mulaney also voices for Mint, Grandpa Andrew, Babe the Blue Ox, and Detective Florez. He is best known for Spider-Man: Into the Spider-Verse and Poker Face.

3) Jessi Klein- Klein voices for Jessi Glaser, a smart and sarcastic girl, and Nick and Andrew's best friend. Klein also voiced for Margaret Daniels. Jessi Klein is famously known for Sleepwalk with Me and Inside Amy Schumer.

4) Ayo Edebiri- Edebiri voices for Missy Foreman-Greenwald, a nerdy and shy girl in the group, who finds it difficult to adjust because of her different upbringing. She is often at the receiving end of Andrew's affection. Ayo Edebiri is known for her work in The Bear and Inside Out 2.

5) Jason Mantzoukas- Brooklyn 99 fame, Pimento, Mantzoukas voices for Jay, another friend in Nick's group. Jay is a brat and obsessed with magic and s*x.

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Big Mouth Season 8: Supporting cast and character guide

1) Maya Rudolph (Bridesmaids, The Good Place): Rudolph voices Connie Cassienga, a female hormone monster

2) Fred Armisen (Wednesday, Easy A): Armisen voices for Elliot Birch, Nick's father

3) Jordan Peele (Us, Nope): Peele voices for two characters, Duke Ellington, a ghost haunting Nick's attic, and Cyrus Foreman-Greenwald, Missy's father

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Who are the voice actor cameos in Big Mouth Season 8?

In addition to the above main and supporting cast, Big Mouth Season 8 will also see some actors in cameo roles. These are as follows:

1) Cynthia Erivo as Missy's body parts (Best known for Wicked)

2) Holly Hunter as Coco, the Compassion Pachyderm (Best known for The Piano)

3) Kristen Wiig (Best known for Bridesmaids)

4) Ali Wong as Ali Chen (Best known for Always Be My Maybe)

5) Natasha Lyonne as Dr. Dunn, the health teacher (Best known for Poker Face, Russian Doll)

6) Quinta Brunson as Quinta (Best known for Abbott Elementary)

7) Steve Buscemi as Mr. Pink (Best known for Fargo)

8) Nathan Fillion as himself and Nate (Best known for The Rookie)

9) Keke Palmer as Rochelle Hillhurst (Best known for Nope)

Big Mouth Season 8 is now streaming on Netflix.

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