Cast of Novocaine (2025)

Last Modified Feb 13, 2025 13:53 EST
Cast of Novocaine (2025)
Novocaine movie trailer visual (Source: Screengrab from the trailer)


The upcoming American action movie Novocaine is directed by Robert Olsen and Dan Berk. The film is set for theatrical release on March 14, 2025, in the United States by Paramount Pictures. In the film, Nathan Caine, played by Jack Quaid, is a bank executive who is incapable of feeling pain. Ray Nicholson, Matt Walsh, Betty Gabriel, and Jacob Batalon are also featured in the movie.


Main cast of Novocaine


Jack Quaid

Cast of Novocaine (2025)
Jack Quaid (Source: Instagram)


The American actor Jack Quaid, best known for his portrayal of Hughie Campbell in “The Boys” is portraying the lead character of Nathan Caine in the film. A mild-mannered introvert with congenital insensitivity to pain (CIP), Nathan Caine has to save his lover when she is kidnapped during a bank heist.


Actor Jack Henry Quaid was born in the United States on April 24, 1992. He had a small part in the dystopian movie The Hunger Games (2012), which marked his acting debut. Quaid also appeared among the main cast of the 2016 drama series Vinyl. In the television shows Star Trek: Lower Decks (2020–2024) and My Adventures with Superman (2023–present), he provided the voice of Brad Boimler and Superman, respectively. He appeared as Richie Kirsch in the slasher movie Scream (2022), as theoretical physicist Richard Feynman in Oppenheimer (2023), and starred in Logan Lucky (2017).


Amber Midthunder

Cast of Novocaine
Amber Midthunder in Legion (Source: Screengrab from the show)


The American actress Amber Midthunder is playing Nathan Caine's (Jack Quaid) girlfriend / co-worker in the film.


Amber's first acting credit was a small role in 2008's Sunshine Cleaning. Before moving to Los Angeles at the age of 17 to look into further acting possibilities, Midthunder went on to work in several productions shot in New Mexico. She featured as Naru in Prey, the fifth edition of the Predator franchise. For her role in Prey, Midthunder was nominated for a Critics' Choice Award for Best Actress in a Limited Series or Movie Made for Television in 2022 and won the Saturn Awards' Breakthrough Performance Award.


Additional cast of Novocaine


Following are the additional cast in the film:

  • Ray Nicholson

  • Jacob Batalon

  • Betty Gabriel

  • Matt Walsh

  • Dominique Maher

  • Evan Hengst

  • Conrad Kemp

  • DeVille Vannik

  • Jessica Leigh Stanley

  • Steve Larter

  • Sean Walker

  • Motsi Tekateka

  • Pieter Stemmet


What is Novocaine about?


The American action film Novocaine revolves around the life of Nathan Caine, played by Jack Quaid. Nathan is a mild-mannered introvert, who struggles with a rare disease called congenital insensitivity to pain (CIP). Nathan uses his weakness to his advantage as he attempts to save his girlfriend after she is taken hostage by a bunch of robbers during a bank robbery.


Also read: When is Novocaine coming out?

FAQs about Novocaine

A. No, Novocaine isn’t a superhero film. It is an action thriller.

A. Jack Quaid is the lead in the upcoming film Novocaine. He portrays the character of Nathan Caine, a guy with a rare disorder called congenital insensitivity to pain (CIP).

A. Yes, Novocaine is a drug. It is an anesthetic commonly used during dentistry.

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